Haystack MRD® receives New York State approval

Bringing Confidence to ASCO 2026

Visit us at Quest Diagnostics® booth 10109

We’re proud to be part of the 2026 American Society of Clinical Oncology (ASCO®) annual meeting, where we’ll present 2 posters featuring new clinical data using Haystack technology.  

Find Confidence in Chicago

We can’t wait to introduce you to our new cast of characters who will show you how Haystack MRD provides confidence in MRD test results.

Learn more about the conference here

Stop by Quest Diagnostics booth 10109

Meet our clinical and executive teams and learn how circulating tumor DNA (ctDNA) testing with Haystack MRD® can help you to:

  • Detect ctDNA with exceptional accuracy
  • Identify patients with residual disease who are at a higher risk of recurrence
  • Gain confident insights for personalized and timely care of your patients

And while you’re there, you’ll meet our new face of Confidence! Be sure to visit our booth to see what we have in store.

See our clinical data

We are proud to collaborate with clinical researchers to present 2 research posters at ASCO this year featuring Haystack technology:

“Diagnostic and predictive utility of peritoneal tumor DNA in gastroesophageal cancer: A prospective multicenter study”

Abstract: 4101
Poster number:
 84

Session: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary

Session time and date: May 30, 9:00 AM-12:00 PM

In this study, a tumor-informed, whole-genome sequencing (WGS) platform was used to detect peritoneal tumor DNA (ptDNA) in patients with gastroesophageal cancers. The results showed that ptDNA accurately diagnosed peritoneal metastasis in this patient cohort, as validated in 10 true negative and 12 true positive patients at a median follow-up time of 17 months. In addition, ptDNA predicted peritoneal recurrence and overall survival outcomes, suggesting the potential for ptDNA to help personalize treatment decisions. Additional data using Haystack MRD to detect ctDNA will be presented at the meeting.

“Intrapatient comparative analysis of tumor-informed ctDNA and ctHPV-DNA in patients with HPV-driven OPSCC”

Abstract: 6075
Poster number: 532

Session: Head and Neck Cancer

Session time and date: May 30, 1:30 PM-4:30 PM

This study compared circulating tumor DNA (ctDNA) and circulating human papillomavirus DNA (ctHPV-DNA) for monitoring patients with HPV-driven oropharyngeal cancers. The goal of the study was to learn whether ctDNA testing could better assess treatment response, help guide management, and detect minimal residual disease (MRD) in these patients. The results showed that the 2 tests were highly consistent in detecting disease, but with distinct kinesthetics for clearance. In patients undergoing treatment, ctDNA cleared several weeks to months earlier than ctHPV. These findings suggest that ctDNA may provide an earlier window into treatment response than ctHPV in patients with HPV-driven oropharyngeal cancers. Further research is ongoing to determine how these 2 tests can be used together for management of HPV-driven oropharyngeal cancers.

About Haystack MRD

Next-generation ctDNA detection with exceptional accuracy for confident MRD reporting

Haystack MRD is a tumor-informed test for detecting ctDNA in solid tumor settings. Superb sensitivity and specificity translate to better MRD detection for greater confidence when making key clinical decisions. 

Purpose-built MRD technology developed by pioneers of cancer research

Haystack MRD was designed specifically for ultrasensitive ctDNA detection when testing for residual or recurrent disease. Better sensitivity helps ensure patients are more likely to receive the right treatment at the right time, which can significantly improve outcomes and quality of life for patients who have been diagnosed with cancer. 

Experience the power of Quest

From early detection screening to diagnosis, monitoring, and beyond, Quest offers routine to advanced testing along the cancer care continuum. Experience the efficiency of working with a single lab to improve the quality and speed of cancer care. 

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Download the whitepaper

Patient access application mailing instructions

Haystack MRD
C/O Quest Diagnostics
2501 S State Hwy 121, Suite 1100
Lewisville, TX 75067

Para solicitar ayuda financiera, complete la solicitud y firme la autocertificación.

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Visit Johns Hopkins School of Medicine to learn more.
Visit Johns Hopkins School of Medicine to learn more.
Visit Johns Hopkins School of Medicine to learn more.